What is bHRT?

Bioidentical hormone replacement therapy uses hormones with the same chemical structure as those produced by the body.

Bioidentical hormone replacement therapy (bHRT) uses hormones that match the chemical structure of the hormones the body produces. They are derived from plant sources, such as yam or soy, and prepared to match estradiol, progesterone, or testosterone.

bHRT vs traditional HRT

Traditional hormone replacement therapy (HRT) often uses synthetic hormones that do not match that structure. bHRT is used as an alternative. It is often described as having fewer side effects and a lower risk of long-term complications. A physician should determine whether it is appropriate for an individual patient.

Potential benefits of bHRT for women

Reported uses for women include the following. Results vary, and treatment should be supervised by a physician.

Relief from menopausal symptoms: bHRT is used to relieve menopausal symptoms such as hot flashes, night sweats, vaginal dryness, and mood swings. Symptom relief is the best-established use of hormone therapy.
Bone health: Declining hormone levels during menopause can reduce bone density and raise the risk of osteoporosis. Helping prevent postmenopausal bone loss is an approved use of some hormone products, and may be prescribed depending on your overall risk profile.
Heart health: Lower estrogen after menopause is associated with a higher risk of heart disease and stroke. bHRT is used to maintain estrogen levels, as part of a plan your physician tailors around your overall risk.
Cognitive function: Declining hormone levels during menopause can affect memory and concentration. bHRT is used to support care for these symptoms, as part of a plan shaped around your overall health.
Breast cancer risk: Breast cancer risk is a conversation to have with your physician before starting any hormone therapy, including bioidentical options. Discuss your personal and family history as part of that decision.
Sexual function: Declining hormone levels during menopause can reduce libido and cause vaginal dryness or discomfort. Relieving those vaginal symptoms is a well-established use of estrogen; testosterone is sometimes prescribed off-label for desire, with a clinician's guidance.
Mood: Depression and anxiety can increase around menopause for some women. Discuss any changes with your physician; hormone therapy is not a substitute for psychiatric care.
Personalized treatment: Dosing can be adjusted to the individual patient. Hormone levels are tested and monitored, and the prescription is changed so the dose matches that patient's needs.